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Unfortunately, the antibody (ID:155882) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



ERBB3 / HER3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

ERBB3 / HER3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Gene Name: v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Family/Subfamily: Protein Kinase , EGF Receptor
Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3
Target Sequences: NM_001982 NP_001973.2 P21860

Publications (2)

1
High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer. Davies S, Holmes A, Lomo L, Steinkamp MP, Kang H, Muller CY, Wilson BS. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 2014 33:402-10. (IHC; Human) [Full Text Article] [PubMed:24901400] [PMC:PMC4153698] Related Antibodies: LS-B2126.
2
Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer. Roßner F, Gieseler C, Morkel M, Royer HD, Rivera M, Bläker H, Dietel M, Schäfer R, Sers C. Oncogenesis. 2016 5:e187. (IHC, WB; Human) [Full Text Article] [PubMed:26779809] [PMC:PMC4728680]

Filtered By: None
Target
erbb3-her3 (194)
Reactivity
Human (174)
Mouse (102)
Rat (65)
Bat (2)
Bovine (13)
Dog (3)
Guinea pig (2)
Hamster (2)
Horse (3)
Monkey (4)
Pig (3)
Rabbit (2)
Rhesus monkey (3)
Wheat (1)
Zebrafish (1)
Application
IHC (82)
IHC-Fr (3)
IHC-P (21)
WB (126)
Flo (36)
ELISA (62)
ICC (14)
IF (34)
Inhb (1)
IP (77)
Neut (7)
Peptide-ELISA (12)
Host
rabbit (100)
mouse (93)
goat (1)
Isotype
IgG (66)
IgG1 (55)
IgG1,k (1)
IgG2a (10)
IgG2a,k (19)
IgG2b (1)
IgG2b,k (2)
Clonality
monoclonal mc (96)
polyclonal pc (98)
Clone
11A4 (1)
1A5 (1)
1A9 (1)
1B11 (1)
1C6 (1)
2A4 (1)
2B11D11 (1)
2B5 (3)
2C3 (2)
2C7 (1)
2E9 (1)
2F11 (1)
2F12 (2)
2F9 (1)
3E10 (1)
3F10F6 (1)
3F12 (1)
4H3 (1)
H3.105.5 (1)
H3.105.5 or AB105 (1)
H3.90.6 (4)
RBT-HER3 (2)
Format
AP Conjugated (11)
APC (2)
APC Conjugated (13)
Azide-free (10)
Biotin Conjugated (16)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (16)
HRP Conjugated (13)
PE Conjugated (14)
Ready-to-Use (1)
Unconjugated (107)
Epitope
aa709-966 (10)
aa707-964 (9)
aa24-55 (8)
C-Terminus (7)
pTyr1328 (5)
pTyr1197 (3)
pTyr1222 (3)
N-Terminus (2)
pTyr1289 (2)
Asp1324 (1)
Glu1218 (1)
Internal (1)
Tyr1328 (1)
aa1-50 (1)
aa1-80 (1)
aa1076-1110 (1)
aa1140-1220 (1)
aa1160-1240 (1)
aa1191-1240 (1)
aa1230-1310 (1)
aa1256-1305 (1)
aa1270-1350 (1)
aa1275-1324 (1)
aa1275-1325 (1)
aa1283-1323 (1)
aa1287-1291 (1)
aa1292-1342 (1)
aa1293-1342 (1)
aa1295-1323 (1)
aa1326-1330 (1)
aa1330-1342 (1)
aa162-181 (1)
aa20-285 (1)
Publications
No (193)
Yes (1)
Showing 1-25 out of 194 results
Anti-ERBB3 / HER3 Antibody (aa1330-1342) IHC-plus™ LS-B2126
Anti-HER3 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2126 concentration 5 ug/ml.
(0.1 ug/ml) Staining of Jurkat lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Goat Polyclonal to Human ERBB3 / HER3
Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 2E9) IHC-plus™ LS-B6035
Anti-HER3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6035 concentration 5 ug/ml.
Anti-HER3 antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6035 concentration 5 ug/ml.

Mouse Monoclonal [clone 2E9] (IgG1,k) to Human ERBB3 / HER3
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 3F10F6) IHC-plus™ LS-B3896
Anti-HER3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3896 dilution 1:200.
Western blot using ERBB3 mouse monoclonal antibody against truncated Trx-ERBB3 recombinant protein (1) and MBP-ERBB3 (aa1175-1275) recombinant protein (2).

Mouse Monoclonal [clone 3F10F6] (IgG1) to Human ERBB3 / HER3
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (aa24-55) LS-C97504
Formalin-fixed and paraffin-embedded human breast carcinoma with ErbB3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Rabbit Polyclonal to Human ERBB3 / HER3
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone H3.90.6, Azide-free) LS-C87996

Mouse Monoclonal [clone H3.90.6] (IgG2a) to Human ERBB3 / HER3
Human
Flo IF IP
Unconjugated, Azide-free
Anti-ERBB3 / HER3 Antibody (phospho-Tyr1222) LS-C35220

Rabbit Monoclonal (IgG) to Human ERBB3 / HER3
Human
ELISA WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 2B5, Biotin) LS-C88060

Mouse Monoclonal [clone 2B5] (IgG1) to Rat ERBB3 / HER3
Mouse, Rat, Human
IP WB
Biotin Conjugated
Anti-ERBB3 / HER3 Antibody (N-Terminus) LS-C368595
Immunohistochemical analysis of HER3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of HER3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human ERBB3 / HER3
Mouse, Human
ICC IF IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 3F12) IHC-plus™ LS-B6036
Anti-HER3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6036 concentration 5 ug/ml.
Anti-HER3 antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6036 concentration 5 ug/ml.

Mouse Monoclonal [clone 3F12] (IgG2a,k) to Human ERBB3 / HER3
Human
ELISA IHC IHC-P
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone H3.105.5) LS-C88048

Mouse Monoclonal [clone H3.105.5] (IgG1) to Human ERBB3 / HER3
Mouse, Human
Flo IF IP
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone H3.90.6, Biotin) LS-C87995

Mouse Monoclonal [clone H3.90.6] (IgG2a) to Human ERBB3 / HER3
Human
Flo IF IP
Biotin Conjugated
Anti-ERBB3 / HER3 Antibody (clone RBT-HER3, Ready-to-Use) LS-C348485
IHC of HER-3 on FFPE Colon Tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.

Rabbit Monoclonal [clone RBT-HER3] (IgG) to Human ERBB3 / HER3
Human
IHC IHC-Fr IHC-P
Unconjugated, Ready-to-Use
Anti-ERBB3 / HER3 Antibody (clone RBT-HER3) LS-C348486
IHC of HER-3 on FFPE Colon Tissue.

Rabbit Monoclonal [clone RBT-HER3] (IgG) to Human ERBB3 / HER3
Human
IHC IHC-Fr IHC-P
Unconjugated
Anti-ERBB3 / HER3 Antibody (aa707-964, Biotin) LS-C421758
Western blot of ERBB3 / HER3 antibody.

Rabbit Polyclonal (IgG) to Mouse ERBB3 / HER3
Mouse
IHC WB
Biotin Conjugated
Anti-ERBB3 / HER3 Antibody (clone 2C7) IHC-plus™ LS-B6037
Anti-HER3 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6037 concentration 10 ug/ml.
Detection limit for recombinant GST tagged ERBB3 is approximately 0.3 ng/ml as a capture antibody.

Mouse Monoclonal [clone 2C7] (IgG2b,k) to Human ERBB3 / HER3
Human
ELISA IHC IHC-P
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 2C3) LS-C88065

Mouse Monoclonal [clone 2C3] (IgG1) to Rat ERBB3 / HER3
Mouse, Rat, Human
IP WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (clone 2B5, Azide-free) LS-C88061

Mouse Monoclonal [clone 2B5] (IgG1) to Rat ERBB3 / HER3
Mouse, Rat, Human
IP WB
Unconjugated, Azide-free
Anti-ERBB3 / HER3 Antibody (Azide-free) LS-C4251

Mouse Monoclonal (IgG2a,k) to Rat ERBB3 / HER3
Mouse, Bovine, Rat, Human
IP WB
Unconjugated, Azide-free
Anti-ERBB3 / HER3 Antibody (C-Terminus) LS-C356018
Immunohistochemical analysis of HER3 (pY1328) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of HER3 (pY1328) staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human ERBB3 / HER3
Zebrafish, Rat, Mouse, Bovine, Human, Monkey
ICC IF IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (C-Terminus) LS-C413197
Immunohistochemical analysis of HER3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of HER3 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human ERBB3 / HER3
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody LS-C486944

Mouse Monoclonal to Human ERBB3 / HER3
Human
ELISA Flo ICC IF
Unconjugated
Anti-ERBB3 / HER3 Antibody (aa1256-1305) LS-C117910
IHC of paraffin-embedded human breast carcinoma tissue, using HER3 (Ab-1289) Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of A549 cells, using HER3 (Ab-1289) Antibody. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human ERBB3 / HER3
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (aa1191-1240) LS-C117909
IHC of paraffin-embedded human brain tissue, using HER3 (Ab-1222) Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of HUVEC cells, using HER3 (Ab-1222) Antibody. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human ERBB3 / HER3
Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (phospho-Tyr1328) LS-C205301
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3 (Phospho-Tyr1328) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence of methanol-fixed MCF7 cells using Her3/ErbB3 (phospho-Tyr1328) antibody.

Rabbit Polyclonal to Human ERBB3 / HER3
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
Anti-ERBB3 / HER3 Antibody (phospho-Tyr1222) LS-C381525

Rabbit Polyclonal (IgG) to Human ERBB3 / HER3
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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