EPRS / PARS

glutamyl-prolyl-tRNA synthetase

Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

EPRS / PARS (5)

Publications

No (5)

Tag

His-T7, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (3)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Purification

Purified (2)

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Mouse EPRS / PARS Protein (Recombinant His-T7, N-terminus) (Gly1007-Tyr1512) - LS-G133471

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

61.3kDa

Price:

10 µg/$277; 50 µg/$420; 200 µg/$837; 100 µg/$670; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113

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Human EPRS / PARS Protein (Recombinant His-T7, N-terminus) (Asp749-Thr956) - LS-G132711

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

26.4kDa

Price:

10 µg/$273; 50 µg/$390; 200 µg/$777; 100 µg/$622; 1 mg/$1,840; 500 µg/$1,398; 5 mg/$2,801; 2 mg/$2,023

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EPRS / PARS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116640

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

170.4 kDa

Price:

100 µg/$710

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Human EPRS / PARS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66324

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

170.4 kDa

Price:

20 µg/$1,107

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Human EPRS / PARS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77460

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

170.4 kDa

Price:

20 µg/$215

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