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EPLIN

LIM domain and actin binding 1

Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.

Gene Name: LIM domain and actin binding 1
Synonyms: LIMA1, SREBP3, EPLIN, LIM domain and actin binding 1
Target Sequences: NM_016357 NP_057441.1 Q9UHB6

Publications (1)

1
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow. Sundvold H, Sundvold-Gjerstad V, Malerød-Fjeld H, Haglund K, Stenmark H, Malerød L. Cell cycle (Georgetown, Tex.). 2016 15:628-43. (WB; Human) [Full Text Article] [PubMed:27104745] [PMC:PMC4845929] Related Antibodies: LS-C134069.

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Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
EPLIN (6)
No (6)
GST (1)
His (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
EPLIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
85 kDa
100 µg/$710
EPLIN Protein - 12.5% SDS-PAGE of human EPLIN stained with Coomassie Blue
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Wheat Germ Extract
GST
91.52 kDa
10 µg/$479; 25 µg/$670
EPLIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
85 kDa
20 µg/$215
EPLIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
85 kDa
20 µg/$150
EPLIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
85 kDa
100 µg/$494
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E. coli
130 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
14.41 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).