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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EPHB2 / EPH Receptor B2

EPH receptor B2

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.

Gene Name: EPH receptor B2
Family/Subfamily: Protein Kinase , Ephrin Receptor
Synonyms: EPHB2, CAPB, Cek5, EK5, ETECK, EPH tyrosine kinase 3, DRT, ELK-related tyrosine kinase, Hek5, EPH-like kinase 5, EPHT3, Nuk, PCBC, Tyrosine-protein kinase TYRO5, Protein-tyrosine kinase HEK5, Tyro5, EPH receptor B2, Ephrin type-B receptor 2, EPTH3
Target Sequences: NM_017449 AAB94602.1 P29323

Filtered by: None
Target
EPHB2 / EPH Receptor B2 (73)
Reactivity
Human (71)
Mouse (26)
Rat (8)
Bovine (1)
Chicken (7)
Dog (1)
Hamster (1)
Horse (1)
Monkey (8)
Pig (1)
Rabbit (8)
Xenopus (1)
Zebrafish (7)
Application
IHC (43)
IHC-P (20)
WB (46)
Flo (14)
ELISA (44)
ICC (9)
IF (12)
IP (7)
Peptide-ELISA (2)
Host
rabbit (49)
mouse (19)
goat (2)
rat (3)
Isotype
IgG (25)
IgG1 (1)
IgG1,k (15)
IgG2a (2)
IgG2b (2)
IgM,k (1)
Clonality
monoclonal mc (22)
polyclonal pc (51)
Clone
12K86 (1)
1F10 (1)
2D12C6 (2)
48CT12.6.4 (1)
Format
AP Conjugated (6)
APC Conjugated (6)
Azide-free (5)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (8)
Unconjugated (32)
Epitope
C-Terminus (9)
aa1021-1050 (8)
aa103-133 (8)
Internal (7)
aa27-551 (3)
960-1040 aa, C-terminal (1)
Amino Acid: 17-200 (1)
aa17-200 (1)
aa226-325 (1)
aa882-893 (1)
aa991-1040 (1)
Publications
No (73)
Showing 1-25 of 73 results

IHC-plus™ EPHB2 / EPH Receptor B2 Antibody (Internal) LS-A2897
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Zebrafish, Rat, Rabbit, Mouse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Anti-EPHB2 / EPH Receptor B2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ EPHB2 / EPH Receptor B2 Antibody (aa17-200, clone 2D12C6) LS-B3904
Mouse Monoclonal [clone 2D12C6] (IgG2b) to Human EPHB2 / EPH Receptor B2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Anti-EPHB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-EPHB2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

EPHB2 / EPH Receptor B2 Antibody (clone 48CT12.6.4) LS-C96481
Mouse Monoclonal [clone 48CT12.6.4] (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
Flo, IHC, IHC-P, WB
Unconjugated
200µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with EPHB2 Monoclonal Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of lysate from EPHB2 protein, using EphB2 Antibody. Antibody was diluted at 1:1000. A goat anti-mouse IgG H&L (HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35ug.

EPHB2 / EPH Receptor B2 Antibody (C-Terminus) LS-C23126
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Mouse, Human
ELISA, IP, WB
Unconjugated
100µg  $635.00

IHC-plus™ EPHB2 / EPH Receptor B2 Antibody (C-Terminus) LS-A2895
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-EPHB2 / EPH Receptor B2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

EPHB2 / EPH Receptor B2 Antibody (aa103-133) LS-C100282
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Mouse, Human
IHC, IHC-P
Unconjugated
400µl  $325.00
EphB2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
EphB2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

EPHB2 / EPH Receptor B2 Antibody LS-C330754
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

EPHB2 / EPH Receptor B2 Antibody (Biotin) LS-C225398
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (FITC) LS-C225399
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (AP) LS-C225395
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (APC) LS-C225397
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (Azide-free, HRP) LS-C225400
Mouse Monoclonal (IgG1,k) to Human EPHB2 / EPH Receptor B2
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody LS-C486156
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Human
IHC, IHC-P
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

EPHB2 / EPH Receptor B2 Antibody (aa882-893) LS-C54793
Goat Polyclonal to Human EPHB2 / EPH Receptor B2
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
Antibody (1 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

EPHB2 / EPH Receptor B2 Antibody (aa27-551, clone 12K86, PE) LS-C182843
Rat Monoclonal [clone 12K86] (IgG2a) to Mouse EPHB2 / EPH Receptor B2
Mouse, Human
Flo
PE Conjugated
100tst  $665.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050) LS-C100283
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with EphB2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with EphB2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050) LS-C327291
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, IF, IHC, WB
Unconjugated
200µl  $590.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, Biotin) LS-C225410
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, FITC) LS-C225411
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, APC) LS-C225409
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, Azide-free, HRP) LS-C225412
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, AP) LS-C225408
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
AP Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody (aa1021-1050, PE) LS-C225413
Rabbit Polyclonal (IgG) to Human EPHB2 / EPH Receptor B2
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200µl  $740.00

EPHB2 / EPH Receptor B2 Antibody LS-C184225
Goat Polyclonal (IgG) to Mouse EPHB2 / EPH Receptor B2
Mouse, Human
ELISA, Flo, ICC, WB
Unconjugated
100µg  $785.00

EPHB2 / EPH Receptor B2 Antibody LS-C100284
Rabbit Polyclonal to Human EPHB2 / EPH Receptor B2
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with EphB2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of EphB2(arrow) using rabbit polyclonal EphB2 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EphB2 gene (Lane 2) (Origene Technologies).
Showing 1-25 of 73 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).