EPHA8 / EPH Receptor A8

EPH receptor A8

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.

☰ Filters

Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

EPHA8 / EPH Receptor A8 (5)

Publications

No (5)

Tag

6His, C-terminus (1)

DDK (Flag)-His, C-terminus (1)

Fc, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Human (2)

Low Endotoxin Level

Low endotoxin level (2)

Select

Human EPHA8 / EPH Receptor A8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88068

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

108.1 kDa

Price:

20 µg/$215

Select

EPHA8 / EPH Receptor A8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111112

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

108.1 kDa

Price:

100 µg/$710

Select

Human EPHA8 / EPH Receptor A8 Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142216

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

60 kDa

Price:

20 µg/$1,107

Select

Human EPHA8 / EPH Receptor A8 Protein (Recombinant 6His, C-terminus) - LS-G146117

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.4 kDa

Price:

10 µg/$308; 50 µg/$502

Select

Human EPHA8 / EPH Receptor A8 Protein (Recombinant Fc, C-terminus) - LS-G146148

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

83.5 kDa

Price:

10 µg/$308; 50 µg/$502

Viewing 1-5 of 5 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.