EPHA5 / EPH Receptor A5

EPH receptor A5

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.

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ELISA Kits (3)

Type

Cell-Based (1)

Custom (1)

Sandwich (1)

Target

EPHA5 / EPH Receptor A5 (3)

Reactivity

Human (2)

Mouse (1)

Rat (2)

Format

96-Well Microplate (2)

96-Well Strip Plate (1)

Publications

No (3)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Tissue Homogenates (1)

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Rat EPHA5 / EPH Receptor A5 (Custom ELISA) ELISA Kit - LS-F50402

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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Human EPHA5 / EPH Receptor A5 (Sandwich ELISA) ELISA Kit - LS-F55021

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$854

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Mouse/Human/Rat EPHA5 / EPH Receptor A5 (Cell-Based ELISA) ELISA Kit - LS-F1965

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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