Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

EPHA4 / EPH Receptor A4

EPH receptor A4

Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.

Gene Name: EPH receptor A4
Family/Subfamily: Protein Kinase , Ephrin Receptor
Synonyms: EPHA4, CEK8, EK8, Ephrin type-A receptor 4, HEK8, SEK, TYRO1, TYRO1 protein tyrosine kinase, Tyrosine-protein kinase TYRO1, EPH receptor A4, EPH-like kinase 8
Target Sequences: NM_004438 NP_004429.1 P54764

Viewing 1-25 of 106 items
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
FITC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
APC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
AP Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
PE Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
EPHA4 / EPH Receptor A4 Antibody - Anti-EPHA4 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
EPHA4 / EPH Receptor A4 Antibody - Human Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
Rabbit Polyclonal to Human EPHA4 / EPH Receptor A4
Human
Flo, IF, IHC-P, WB
Unconjugated
200µl   $425.00
EPHA4 / EPH Receptor A4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human EPHA4 / EPH Receptor A4
Human
IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00

Viewing 1-25 of 106 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).