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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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EPHA2 / EPH Receptor A2

EPH receptor A2

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

Gene Name: EPH receptor A2
Family/Subfamily: Protein Kinase , Ephrin Receptor
Synonyms: EPHA2, CTPA, EPH receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, ECK, Sek-2, ARCC2, Soluble EPHA2 variant 1, CTPP1
Target Sequences: NM_004431 NP_004422.2 P29317


EPHA2 / EPH Receptor A2 Antibody - Anti-EPHA2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Mouse Monoclonal [clone 3D7] (IgG2b,k) to Human EPHA2 / EPH Receptor A2
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
EPHA2 / EPH Receptor A2 Antibody - Anti-EPHA2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human EPHA2 / EPH Receptor A2
Mouse, Dog, Bovine, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg   0.5mg/ml   $425.00
EPHA2 / EPH Receptor A2 Antibody - Anti-EPHA2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Mouse Monoclonal [clone 1B3C7] (IgM) to Human EPHA2 / EPH Receptor A2
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $425.00
Select
Mouse Monoclonal [clone GM5H5] (IgG1) to Human EPHA2 / EPH Receptor A2
Human
ELISA, Flo, IF
Unconjugated
100µg   1mg/ml   $575.00
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Mouse Monoclonal (IgG2a) to Human EPHA2 / EPH Receptor A2
Mouse, Dog, Bovine, Human
Flo, ICC, WB
Unconjugated
100µg   $680.00
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Mouse Monoclonal [clone D7] (IgG1) to Human EPHA2 / EPH Receptor A2
Human
Flo
PE Conjugated
100tst   $665.00
EPHA2 / EPH Receptor A2 Antibody - Western blot of EphA2 Antibody (pS897) antibody (RB21717) pre-incubated without(lane 1) and with(lane 2) FBS in HA cell line lysate. EphA2 Antibody (pS897) (arrow) was detected using the purified antibody(Kindly provided by Dr. John Wu).
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Rabbit Polyclonal to Human EPHA2 / EPH Receptor A2
Human
DB, WB
Unconjugated
400µl   $325.00
EPHA2 / EPH Receptor A2 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Rabbit Polyclonal to Human EPHA2 / EPH Receptor A2
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
Unconjugated
200µl   $590.00
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Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Hamster, Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Human
DB, ELISA, WB
Unconjugated
200µl   $590.00
EPHA2 / EPH Receptor A2 Antibody - Western blot analysis of lysates from brain tissue, using phospho-EphA2 (Phospho-Tyr772) antibody.
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Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Mouse, Human
ELISA, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rat Monoclonal (IgG2b) to Mouse EPHA2 / EPH Receptor A2
Mouse
Flo
APC Conjugated
100tst   $710.00
Select
Rabbit Monoclonal [clone 301] (IgG) to Mouse EPHA2 / EPH Receptor A2
Mouse
Flo
PE Conjugated
25tst   0.1mg/ml   $235.00; 100tst   0.1mg/ml   $315.00
Select
Rabbit Monoclonal [clone 301] (IgG) to Mouse EPHA2 / EPH Receptor A2
Mouse
Flo
FITC Conjugated
25tst   0.1mg/ml   $225.00; 100tst   0.1mg/ml   $285.00
Select
Rabbit Monoclonal [clone 101] (IgG) to Mouse EPHA2 / EPH Receptor A2
Mouse
Flo
APC Conjugated
25tst   0.1mg/ml   $235.00; 100tst   0.1mg/ml   $315.00
EPHA2 / EPH Receptor A2 Antibody - ICC/IF analysis of EPHA2 in HeLa cell line, stained monoclonal anti-human EPHA2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of EPHA2 in A431 cell line, stained monoclonal anti-human EPHA2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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Mouse Monoclonal [clone AT66G9] (IgG2b,k) to Human EPHA2 / EPH Receptor A2
Human
ELISA, Flo, ICC, WB
Unconjugated
50µl   1mg/ml   $275.00; 100µl   1mg/ml   $345.00
EPHA2 / EPH Receptor A2 Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
Rabbit Polyclonal (IgG) to Human EPHA2 / EPH Receptor A2
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
EPHA2 / EPH Receptor A2 Antibody - Immunofluorescence imaging on fixed LL/2 cells.
Select
Human Recombinant Monoclonal [clone 1C1] (IgG1,k) to Human EPHA2 / EPH Receptor A2
Human
Agon, ELISA, Flo, IF, WB
Unconjugated
0.2mg   1mg/ml   $405.00
EPHA2 / EPH Receptor A2 Antibody - Immunofluorescence imaging on fixed LL/2 cells.
Select
Rabbit Recombinant Monoclonal [clone 1C1] (IgG,k) to Human EPHA2 / EPH Receptor A2
Human
Agon, ELISA, Flo, IF, WB
Unconjugated
0.2mg   1mg/ml   $405.00
Viewing 1-25 of 120 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).