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EPCAM

epithelial cell adhesion molecule

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Gene Name: epithelial cell adhesion molecule
Synonyms: EPCAM, 323/A3, ACSTD1, 17-1A, CD326, EGP, EGP34, Epithelial glycoprotein, GA733-2, HNPCC8, Ep-CAM, ESA, HEGP314, KS 1/4 antigen, KS1/4, KSA, M1S2, MIC18, MK-1, MH99, TROP1, TACST-1, TACSTD1, CD326 antigen, CO-17A, DIAR5, EGP-2, EGP314, EGP40, Epithelial glycoprotein 314, HEA125, Ly74, M4S1
Target Sequences: NM_002354 NP_002345.2 P16422

Publications (5)

1
Nuclear signalling by tumour-associated antigen EpCAM. Maetzel D, Denzel S, Mack B, Canis M, Went P, Benk M, Kieu C, Papior P, Baeuerle PA, Munz M, Gires O. Nature cell biology. 2009 11:162-71. (IP) [PubMed:19136966]
2
Both human and mouse mesenchymal stem cells promote breast cancer metastasis. Albarenque SM, Zwacka RM, Mohr A. Stem cell research. 2011 7:163-71. [PubMed:21763624]
3
An improved method for isolation of epithelial and stromal cells from the human endometrium. Masuda A, Katoh N, Nakabayashi K, Kato K, Sonoda K, Kitade M, Takeda S, Hata K, Tomikawa J. The Journal of reproduction and development. 2016 62:213-8. (Flo; Human) [Full Text Article] [PubMed:26853786] [PMC:PMC4848580] Related Antibodies: LS-C112552.
4
A role for intestinal TLR4-driven inflammatory response during activity-based anorexia. Belmonte L, Achamrah N, Nobis S, Guérin C, Riou G, Bôle-Feysot C, Boyer O, Richard V, Rego JC, Déchelotte P, Goichon A, Coëffier M. Scientific reports. 2016 October;6:35813. (Mouse) [Full Text Article] [PubMed:27779218] [PMC:PMC5078809]
5
Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine. Roulois D, Deshayes S, Guilly MN, Nader JS, Liddell C, Robard M, Hulin P, Ouacher A, Le Martelot V, Fonteneau JF, Grégoire M, Blanquart C, Pouliquen DL. Oncotarget. 2016 June;7:34664-87. (Human) [Full Text Article] [PubMed:27129173] [PMC:PMC5085183] Related Antibodies: LS-C331328.
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☰ Filters
Products
Proteins (25)
Over-Expression Lysate (2)
Recombinant (23)
EPCAM (25)
No (25)
6His, C-terminus (2)
6His-SUMO, N-terminus (1)
DDK,C-terminus (1)
Fc (2)
Fc, C-terminus (4)
GST (1)
His (4)
His, N-terminus (2)
His,C-terminus (1)
His-AVI, C-terminus (1)
His-GST, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Chicken (1)
Human (16)
Mouse (4)
Pig (1)
Rat (2)
293T Cells (1)
E. coli (8)
HEK 293 Cells (7)
Human Cells (5)
Mammalian Cells (2)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purified (7)
Low endotoxin level (13)
EPCAM Protein - 12.5% SDS-PAGE of human EPCAM stained with Coomassie Blue
Select
Wheat Germ Extract
GST
60.17 kDa
2 µg/$439
EPCAM Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
Mammalian Cells
Fc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$248; 50 µg/$321; 500 µg/$761; 1 mg/$1,067
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.2 kDa
100 µg/$721
EPCAM Protein - Recombinant Mouse EpCAM Protein (His Tag)-Elabscience
Select
E. coli
His, N-terminus
27.65 kDa
20 µg/$270; 100 µg/$390
EPCAM Protein
Select
Sf9 Cells
DDK,C-terminus
29.5 kDa
20 µg/$677
EPCAM Protein - Recombinant Human EpCAM Protein (His Tag)-Elabscience
Select
E. coli
His, N-terminus
27.42 kDa
20 µg/$270; 100 µg/$390
EPCAM Protein - Recombinant  Epithelial Cell Adhesion Molecule By SDS-PAGE
Select
E. coli
His-T7
32.2 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
EPCAM Protein - Recombinant  Epithelial Cell Adhesion Molecule By SDS-PAGE
Select
E. coli
His-T7
32.2 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
EPCAM Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
29 kDa
100 µg/$721
EPCAM Protein - Purified recombinant protein EPCAM was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
32.7 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
34.9 kDa
20 µg/$150
EPCAM Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.9 kDa
100 µg/$494
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
54.8 kDa
100 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
29 kDa
100 µg/$721; 1 mg/$4,701
Select
E. coli
180 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
19.91 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.8 kDa
10 µg/$248; 50 µg/$317
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.5 kDa
10 µg/$266; 50 µg/$339
Select
HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.4 kDa
10 µg/$262; 50 µg/$361
Select
HEK 293 Cells
His-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.2 kDa
20 µg/$416; 100 µg/$910
Select
HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.43kD
10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
54 kDa
100 µg/$721
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.5kD
10 µg/$266; 50 µg/$343; 500 µg/$1,377; 1 mg/$1,765
EPCAM Protein - Recombinant Epithelial Cell Adhesion Molecule (EPCAM) by SDS-PAGE
Select
E. coli
His-GST, N-terminus
62kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).