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Eosinophil Peroxidase / EPX

eosinophil peroxidase

Eosinophil Peroxidase / EPX is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.

Gene Name:	eosinophil peroxidase
Synonyms:	EPX, Eosinophil peroxidase, EPER, EPP, EPX-PEN
Target Sequences:	NM_000502 NP_000493.1 P11678

Publications (1)

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia. Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler. PloS one. 2020 October;15:e0240120. [Full Text Article] [PubMed:33048949] [PMC:PMC7553312] Related Antibodies: LS-C354350.

Eosinophil Peroxidase / EPX Protein - 12.5% SDS-PAGE of human EPX stained with Coomassie Blue

Human Eosinophil Peroxidase / EPX Protein (Recombinant GST) (Full Length) - LS-G31098

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

105.6 kDa

Price:

2 µg/$439

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Products: Proteins

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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