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Eomesodermin / EOMES
eomesodermin
Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.
| Gene Name: | eomesodermin |
| Synonyms: | EOMES, Eomesodermin, Eomesodermin homolog, T box, brain, 2, T-box brain protein 2, T-box brain2, T-brain-2, TBR-2, TBR2 |
| Target Sequences: | NM_005442 NP_005433.2 O95936 |
Publications (2)
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