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ENTPD4 / LALP70

ectonucleoside triphosphate diphosphohydrolase 4

Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.

Gene Name: ectonucleoside triphosphate diphosphohydrolase 4
Synonyms: ENTPD4, KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, Lysosomal apyrase-like 1, Uridine-diphosphatase, Golgi luminal UDPase, NTPDase 4, UDPase
Target Sequences: NM_004901 NP_004892.1 Q9Y227

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).