Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

Endothelin 3 / EDN3

endothelin 3

Endothelin 3 / EDN3 is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: endothelin 3
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: EDN3, Endothelin-3, ET3, Endothelin 3, Preproendothelin-3, WS4B, ET-3, HSCR4, PPET3
Target Sequences: NM_000114 NP_000105.1 P14138


Endothelin 3 / EDN3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal [clone 2A6-2A4] (IgG1,k) to Human Endothelin 3 / EDN3
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µg   0.5mg/ml   $495.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Rat, Pig, Human
IF, IHC
Unconjugated
50µl   $495.00
Endothelin 3 / EDN3 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using EDN3 Polyclonal Antibody at dilution of 1:30.
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, IHC
Unconjugated
20µl   0.5mg/ml   $205.00; 60µl   0.5mg/ml   $235.00; 120µl   0.5mg/ml   $295.00; 200µl   0.5mg/ml   $395.00
Endothelin 3 / EDN3 Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Endothelin 3 / EDN3 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-EDN3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Select
Mouse Monoclonal [clone OTI3E10] (IgG1) to Human Endothelin 3 / EDN3
Human
IHC
Unconjugated
100µl   1mg/ml   $345.00
Endothelin 3 / EDN3 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-EDN3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
Select
Mouse Monoclonal [clone OTI3E10] (IgG1) to Human Endothelin 3 / EDN3
Human
IHC
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal to Human Endothelin 3 / EDN3
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $385.00
Endothelin 3 / EDN3 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using EDN3 Polyclonal Antibody at dilution of 1:50.
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, IHC
Unconjugated
20µl   0.8mg/ml   $205.00; 60µl   0.8mg/ml   $235.00; 120µl   0.8mg/ml   $295.00; 200µl   0.8mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Mouse, Human
IHC
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Rabbit, Pig, Human
ELISA
Unconjugated
400µg   $725.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
WB
AP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
WB
APC Conjugated
100µl   $755.00
Endothelin 3 / EDN3 Antibody - Endothelin 3 / EDN3 antibody Western Blot of PANC1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human Endothelin 3 / EDN3
Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Endothelin 3 / EDN3 Antibody - EDN3 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The EDN3 antibody detected the EDN3 protein (arrow).
Select
Rabbit Polyclonal to Human Endothelin 3 / EDN3
Human
WB
Unconjugated
400µl   $325.00
Endothelin 3 / EDN3 Antibody - EDN3 / Endothelin 3 antibody Western blot of Fetal Kidney lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human Endothelin 3 / EDN3
Pig, Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Endothelin 3 / EDN3 Antibody - Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. Endothelin 3 / EDN3 antibody diluted at 1:1000.
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
WB
Unconjugated
100µl   0.52mg/ml   $355.00
Endothelin 3 / EDN3 Antibody - Western blot analysis of extracts of various cell lines, using EDN3 antibody.
Select
Rabbit Polyclonal (IgG) to Human Endothelin 3 / EDN3
Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Viewing 1-25 of 43 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).