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ELMO1 / ELMO 1

engulfment and cell motility 1

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

Gene Name: engulfment and cell motility 1
Synonyms: ELMO1, Ced-12 homolog 1, ELMO-1, Engulfment and cell motility 1, KIAA0281, Protein ced-12 homolog, CED-12, CED12
Target Sequences: NM_014800 NP_055615.8 Q92556

Publications (1)

1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112]

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Products
Proteins (11)
Over-Expression Lysate (6)
Recombinant (5)
ELMO1 / ELMO 1 (11)
No (11)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (8)
Human (8)
293T Cells (3)
E. coli (1)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (1)
ELMO1 / ELMO 1 Protein - Purified recombinant protein ELMO1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
83.6 kDa
20 µg/$1,107
ELMO1 / ELMO 1 Protein - Purified recombinant protein ELMO1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
28.6 kDa
20 µg/$1,107
ELMO1 / ELMO 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
83.83 kDa
20 µg/$150
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
83.6 kDa
20 µg/$215
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.6 kDa
20 µg/$150
ELMO1 / ELMO 1 Protein - 12.5% SDS-PAGE of human ELMO1 stained with Coomassie Blue
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Wheat Germ Extract
GST
110.2 kDa
10 µg/$479; 25 µg/$670
ELMO1 / ELMO 1 Protein
Select
E. coli
His, N-Terminal
28.6 kDa
50 µg/$419
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.6 kDa
100 µg/$494
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
83.6 kDa
100 µg/$710
ELMO1 / ELMO 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
83.83 kDa
100 µg/$494
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).