ELL / MEN

elongation factor RNA polymerase II

Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ELL / MEN (4)

Publications

No (4)

Tag

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human ELL / MEN Protein (Recombinant GST, N-terminus) (aa522-619) - LS-G60659

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ELL / MEN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75694

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.1 kDa

Price:

20 µg/$150

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Human ELL / MEN Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144836

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

94.1 kDa

Price:

50 µg/$419

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ELL / MEN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115246

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.1 kDa

Price:

100 µg/$494

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