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ELK3 / NET
ELK3, ETS-domain protein (SRF accessory protein 2)
ELK3 / NET is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants.
| Gene Name: | ELK3, ETS-domain protein (SRF accessory protein 2) |
| Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
| Synonyms: | ELK3, ERP, Ets-domain protein elk-3, ETS-related protein NET, ETS-domain protein, NET, SAP-2, SAP2, SRF accessory protein 2, ETS-related protein ERP |
| Target Sequences: | NM_005230 NP_005221.2 P41970 |
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