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EIF4ENIF1 / 4E-T
eukaryotic translation initiation factor 4E nuclear import factor 1
EIF4ENIF1 / 4E-T is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| Synonyms: | EIF4ENIF1, 4E-T, EIF4E transporter, EIF4E-transporter, Clast4 |
| Target Sequences: | NM_019843 |
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