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EIF4A2

eukaryotic translation initiation factor 4A2

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Gene Name:	eukaryotic translation initiation factor 4A2
Synonyms:	EIF4A2, BM-010, EIF-4A-II, EIF4A, EIF4A-II, EIF4F, DDX2B
Target Sequences:	NM_001967 NP_001958.2 Q14240

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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