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EIF3E

eukaryotic translation initiation factor 3, subunit E

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

Gene Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: EIF3E, EIF3-p46, INT6, EIF-3 p48, EIF3-P48, EIF3S6
Target Sequences: NM_001568 NP_001559.1 P60228

☰ Filters
Antibodies (33)
Proteins (6)
Over-Expression Lysate (2)
Primary (33)
Recombinant (4)
EIF3E (39)
Human (32)
Mouse (16)
Rat (12)
Bat (7)
Bovine (9)
Chicken (3)
Chimpanzee (6)
Dog (9)
Gibbon (6)
Guinea pig (6)
Hamster (1)
Horse (7)
Monkey (9)
Orangutan (6)
Pig (7)
Rabbit (7)
Xenopus (3)
Zebrafish (6)
IHC (12)
IHC-P (7)
WB (32)
ELISA (11)
ICC (1)
IF (6)
IP (4)
Peptide-ELISA (2)
rabbit (32)
goat (1)
Product Group
IHCPlus (3)
IgG (21)
polyclonal pc (33)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (22)
aa248-276 (7)
aa36-85 (4)
aa360-409 (4)
C-Terminus (2)
aa1-445 (1)
aa1-50 (1)
aa425-436 (1)
aa50-100 (1)
No (39)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
EIF3E Antibody - Anti-EIF3E antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EIF3E Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
EIF3E Antibody - Anti-EIF3E antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EIF3E Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
EIF3E Antibody - Anti-EIF3E antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EIF3E Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
EIF3E Antibody - Anti-EIF3E antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EIF3E Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
EIF3E Antibody - Anti-EIF3E antibody IHC staining of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EIF3E Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$485
EIF3E Antibody - Human Pancreas, Formalin-Fixed, Paraffin-Embedded (FFPE)
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EIF3E Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µg/$485
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EIF3E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
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EIF3E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
EIF3E Antibody - Immunofluorescence analysis of HeLa cells.
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EIF3E Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
EIF3E Antibody - Immunofluorescent analysis of eIF3E staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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EIF3E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
EIF3E Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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EIF3E Rabbit anti-Human Polyclonal (aa1-445) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
EIF3E Antibody - Detection of Human eIF3E by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-eIF3E used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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EIF3E Rabbit anti-Human Polyclonal (aa50-100) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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EIF3E Rabbit anti-Human Polyclonal Antibody
IF, WB
Unconjugated
50 µg/$440; 100 µg/$480
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EIF3E Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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EIF3E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
EIF3E Antibody - Anti-eIF3S6/Int6 Antibody - Western Blot. Western blot of affinity purified anti-eIF3S6/Int6 antibody shows detection of endogenous eIF3S6/Int6 in whole cell extracts from murine (HC-11 and NIH3T3), monkey (CV-1 and Cos-1), and human (HEK293T) cell lines as well as over-expressed eIF3S6/Int6 (control transfected flag-tagged Int6). The identity of the higher and lower molecular weight bands is unknown. The band at ~48 kD, indicated by the arrowhead, corresponds to flag-tagged EIF3S6/Int6. Primary antibody was used at 1:1000. Personal communication, J. Lee, NCI, Bethesda, MD.
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EIF3E Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Human, Monkey
ELISA, WB
Unconjugated
100 µg/$567
EIF3E Antibody - Western blot using the affinity purified anti-eIF3S6/Int6 antibody shows detection of endogenous eIF3S6/Int6 in whole cell extracts from murine (HC-11 and NIH3T3), monkey (CV-1 and Cos-1), and human (HEK293T) cell lines as well as over-expressed eIF3S6/Int6 (control transfected flag-tagged Int6).  The identity of the higher and lower molecular weight bands is unknown.  The band at ~48 kDa, indicated by the arrowhead, corresponds to flag-tagged EIF3S6/Int6.  Primary antibody was used at 1:1000.
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EIF3E Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Human, Monkey
ELISA, WB
Unconjugated
25 µl/$304
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EIF3E Rabbit anti-Human Polyclonal (aa248-276) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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EIF3E Rabbit anti-Human Polyclonal (aa248-276) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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EIF3E Rabbit anti-Human Polyclonal (aa248-276) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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EIF3E Rabbit anti-Human Polyclonal (aa248-276) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
EIF3E Rabbit anti-Human Polyclonal (aa248-276) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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EIF3E Rabbit anti-Human Polyclonal (aa248-276) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
EIF3E Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
EIF3E Antibody - Western blot analysis of EIF3E using COLO205 whole cells lysates
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EIF3E Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 39 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).