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EIF3C / EIF3S8

eukaryotic translation initiation factor 3, subunit C

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Gene Name: eukaryotic translation initiation factor 3, subunit C
Synonyms: EIF3C, EIF3 p110, EIF3S8, EIF3-P110
Target Sequences: NM_003752 NP_003743.1 Q99613

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
EIF3C / EIF3S8 (6)
No (6)
Myc-DDK (Flag) (6)
Human (4)
293T Cells (2)
HEK 293 Cells (4)
EIF3C / EIF3S8 Protein - Purified recombinant protein EIF3C was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
105.2 kDa
20 µg/$1,107
EIF3C / EIF3S8 Protein - Purified recombinant protein EIF3C was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
105.2 kDa
20 µg/$1,107
EIF3C / EIF3S8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
105.2 kDa
100 µg/$494
EIF3C / EIF3S8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
105.2 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
105.2 kDa
20 µg/$150
EIF3C / EIF3S8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
105.2 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).