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EIF2A / EIF2 Alpha

eukaryotic translation initiation factor 2A, 65kDa

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.

Gene Name:	eukaryotic translation initiation factor 2A, 65kDa
Synonyms:	EIF2A, CDA02, EIF2 alpha, MSTP004, MSTP089, EIF-2A, MST089
Target Sequences:	NM_032025 NP_114414.2 Q9BY44

Publications (1)

Tumor necrosis factor-a triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial- and non-mitochondrial-dependent pathways. Denis Selimovic, Renate U Wahl, Emmanuelle Ruiz, Rizwan Aslam, Thomas W Flanagan, Sofie-Yasmin Hassan, Simeon Santourlidis, Youssef Haikel, Paul Friedlander, Mosaad Megahed, Emad Kandil, Mohamed Hassan. International journal of oncology. 2019 December;55:1324-1338. [Full Text Article] [PubMed:31638203]

Human EIF2A / EIF2 Alpha (Sandwich ELISA) ELISA Kit - LS-F38239

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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