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EFCAB6

EF-hand calcium binding domain 6

EFCAB6 is a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name:	EF-hand calcium binding domain 6
Synonyms:	EFCAB6, DJ-1-binding protein, DJBP, HSCBCIP1, KIAA1672, DJ185D5.1, FLJ23588
Target Sequences:	NM_022785 NP_073622.2 Q5THR3

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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