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EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1D is a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
| Gene Name: | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| Family/Subfamily: | Translation factor |
| Synonyms: | EEF1D, Antigen NY-CO-4, EF-1D, EF-1-delta, Elongation factor 1-delta, FP1047, EF1D |
| Target Sequences: | NM_032378 NP_115754.3 P29692 |
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