EDNRB / Endothelin B Receptor

endothelin receptor type B

The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described; the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct.

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Products

Proteins (12)

Type

Over-Expression Lysate (6)

Recombinant (6)

Target

EDNRB / Endothelin B Receptor (12)

Product Group

Alzheimer's Disease (12)

Publications

No (12)

Tag

10His, C-terminus (1)

Fc (1)

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (7)

Species

Human (9)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (4)

Human Cells (1)

Wheat Germ Extract (3)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human EDNRB / Endothelin B Receptor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65515

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.9 kDa

Price:

20 µg/$1,107

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Human EDNRB / Endothelin B Receptor Protein (Recombinant 10His, C-terminus) (aa27-442) - LS-G57427

Source:

E. coli

Tag:

10His, C-terminus

Biological Activity:

Biologically active

Price:

100 µg/$1,293; 20 µg/$854

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Human EDNRB / Endothelin B Receptor Protein (Recombinant GST, N-terminus) (aa27-101) - LS-G58404

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human EDNRB / Endothelin B Receptor Protein (Recombinant GST, N-terminus) (aa27-101) - LS-G58406

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75721

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.64 kDa

Price:

20 µg/$150

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Human EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75723

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.64 kDa

Price:

20 µg/$150

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Human EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75724

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.71 kDa

Price:

20 µg/$215

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Human EDNRB / Endothelin B Receptor Protein (Recombinant Fc) (Met1-Lys101) - LS-G97407

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

34.4 kDa

Price:

100 µg/$843

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Human EDNRB / Endothelin B Receptor Protein (Recombinant GST) (Full Length) - LS-G28297

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76 kDa

Price:

2 µg/$439

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EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124410

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.64 kDa

Price:

100 µg/$494

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EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98921

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.64 kDa

Price:

100 µg/$494

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EDNRB / Endothelin B Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116961

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.71 kDa

Price:

100 µg/$710

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