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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EDAR

ectodysplasin A receptor

EDAR is a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Gene Name: ectodysplasin A receptor
Synonyms: EDAR, Ectodysplasin-A receptor, ED1R, EDA-A1 receptor, EDA1R, DL, Downless, mouse, homolog of, ED3, EDA3, ECTD10A, ECTD10B, Ectodysplasin A receptor, ED5, Downless homolog, Ectodermal dysplasia receptor, EDA-A1R, HRM1
Target Sequences: NM_022336 NP_071731.1 Q9UNE0

Filtered by: None
Type
Over-Expression Lysate (2)
Recombinant (9)
Target
EDAR (11)
Tag
Fc (1)
Fc,C-terminus (1)
GST,N-terminus (1)
hIgG-His-tag, C-terminus (1)
His (2)
His, N-Terminal (1)
Human IgG1 Fc (1)
Myc + DDK (3)
Species
Human (9)
Mouse (1)
Source
293T Cells (1)
CHO Cells (1)
E. coli (2)
HEK 293 Cells (2)
Human Cells (3)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purification
Purified (6)
Low Endotoxin Level
Low endotoxin level (4)
Biologically Active
Biologically active (1)
Publications
No (11)
Showing 1-11 of 11 results

Human EDAR Protein (Recombinant hIgG-His-tag, C-terminus) (aa27-187) - LS-G134664
Sf9 Cells
hIgG-His-tag, C-terminus
45.6kDa
2µg  $195.00; 10µg  $255.00; 1mg  $5,460.00

Human EDAR Protein (Recombinant GST,N-terminus) (aa64-178) - LS-G61675
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Human EDAR Protein (Recombinant His, N-Terminal) (aa27-448) - LS-G134642
E. coli
His, N-Terminal
48.2kDa
5µg  $195.00; 20µg  $255.00; 1mg  $3,780.00

EDAR Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G101800
HEK 293 Cells
Myc + DDK
45.8 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Mouse EDAR Protein (Recombinant Fc,C-terminus) (Glu27-Ile189) - LS-G40133
Human Cells
Fc,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7kD
10µg  $225.00; 50µg  $335.00; 500µg  $1,605.00; 1mg  $2,310.00

Human EDAR Protein (Recombinant Myc + DDK) (Full Length) - LS-G70665
HEK 293 Cells
Myc + DDK
45.8 kDa
20µg  $890.00
Purified recombinant protein EDAR was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human EDAR Protein (Recombinant His) (Met1-Ile189) - LS-G98570
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
19 kDa
100µg  $545.00; 200µg  $815.00

Human EDAR Protein (Recombinant Fc) (Met1-Ile189) - LS-G97404
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
44.6 kDa
100µg  $545.00; 200µg  $815.00

Human EDAR Protein (Recombinant Human IgG1 Fc) (aa27-183) - LS-G3946
CHO Cells
Human IgG1 Fc
Biologically active
Less than 0.01 EU/µg protein (determined by LAL method).
~50kDa (SDS-PAGE)
50µg  $325.00

Human EDAR Protein (Recombinant His) - LS-G3082
E. coli
His
100µg 0.25mg/ml  $365.00; 0.5mg 0.25mg/ml  $935.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human EDAR Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G87696
293T Cells
Myc + DDK
45.8 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-11 of 11 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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