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ECSIT

ECSIT signalling integrator

Activation of NF-kB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2) to kinases such as IRAK (3) and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.

Gene Name: ECSIT signalling integrator
Synonyms: ECSIT, ECSIT homolog (Drosophila), Protein SITPEC, SITPEC
Target Sequences: NM_016581 NP_057665.2 Q9BQ95

☰ Filters
Antibodies (26)
Proteins (7)
Over-Expression Lysate (2)
Primary (26)
Recombinant (5)
ECSIT (33)
Human (21)
Mouse (11)
Rat (4)
Bat (3)
Bovine (3)
Gibbon (3)
Hamster (3)
Horse (3)
Monkey (3)
Rabbit (3)
IHC (7)
IHC-P (3)
WB (23)
ELISA (12)
IF (1)
Peptide-ELISA (1)
rabbit (26)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (26)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (15)
aa396-425 (7)
aa241-290 (4)
aa51-100 (4)
C-Terminus (1)
aa185-431 (1)
No (33)
GST (2)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
ECSIT Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ECSIT Rabbit anti-Mouse Polyclonal (aa241-290) Antibody
Mouse
WB
Unconjugated
100 µl/$397
ECSIT Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa241-290) (Biotin) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
ECSIT Antibody - NIH 3T3 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa241-290) (FITC) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$442
ECSIT Antibody - Anti-ECSIT antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ECSIT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ECSIT Antibody - Immunohistochemistry of paraffin-embedded human small intestine using antibody at 1:100 dilution.
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ECSIT Rabbit anti-Human Polyclonal (aa185-431) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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ECSIT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$412
ECSIT Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using ECSIT Polyclonal Antibody at dilution of 1:70(×200)
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ECSIT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ECSIT Antibody - Fluorescent confocal image of HeLa cell stained with ECSIT Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with ECSIT primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). ECSIT immunoreactivity is localized to Cytoplasm and Nucleus significantly.
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ECSIT Rabbit anti-Human Polyclonal (aa396-425) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
ECSIT Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
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ECSIT Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ECSIT Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using ECSIT Polyclonal Antibody at dilution of 1:75(×200)
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ECSIT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ECSIT Rabbit anti-Human Polyclonal (aa396-425) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ECSIT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ECSIT Rabbit anti-Human Polyclonal Antibody
Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ECSIT Antibody - ECSIT antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa51-100) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ECSIT Antibody - ECSIT antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa51-100) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$469
ECSIT Antibody - ECSIT antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa51-100) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$469
ECSIT Antibody - ECSIT antibody Western blot of Mouse Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ECSIT Rabbit anti-Mouse Polyclonal (aa51-100) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$469
Select
ECSIT Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
ECSIT Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$649
ECSIT Antibody - Western blot analysis of ECSIT expression in HepG2 (A); mouse kidney (B); mouse heart (C) whole cell lysates.
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ECSIT Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Viewing 1-25 of 33 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).