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ECaC / TRPV5

transient receptor potential cation channel, subfamily V, member 5

Constitutively active calcium selective cation channel thought to be involved in Ca2+ reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca2+-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Gene Name:	transient receptor potential cation channel, subfamily V, member 5
Family/Subfamily:	Ion Channel , Calcium channel - TRP
Synonyms:	TRPV5, CAT2, Calcium transport protein 2, Calcium transporter 2, ECAC1, Epithelial calcium channel 1, ECaC, OTRPC3, Osm-9-like TRP channel 3
Target Sequences:	NM_019841 NP_062815.3 Q9NQA5

ECaC / TRPV5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.

Human ECaC / TRPV5 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G62841

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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