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EAR2 / NR2F6

nuclear receptor subfamily 2, group F, member 6

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).

Gene Name: nuclear receptor subfamily 2, group F, member 6
Family/Subfamily: NHR , NR2 Hepatocyte NF4-like
Synonyms: NR2F6, Erba related 2, ERBAL2, EAR-2, EAR2, ERBA-related gene-2, V-erbA-related protein 2
Target Sequences: NM_005234 AAH02669.3 P10588

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Products
Antibodies (59)
Primary (59)
EAR2 / NR2F6 (59)
Human (58)
Mouse (30)
Rat (31)
Bat (15)
Bovine (17)
Chimpanzee (9)
Dog (22)
Guinea pig (4)
Hamster (7)
Monkey (19)
Pig (17)
Xenopus (7)
Zebrafish (11)
IHC (25)
IHC-P (21)
WB (36)
Flo (1)
ELISA (12)
ICC (1)
IF (5)
IP (1)
Peptide-ELISA (2)
rabbit (52)
mouse (6)
goat (1)
Product Group
IHCPlus (14)
PathPlus Cancer (1)
IgG (34)
IgG2a (6)
monoclonal mc (6)
polyclonal pc (53)
EM-51 (1)
OTI2C9 (2)
OTI2H4 (2)
AP Conjugated (3)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (8)
Carrier-free (2)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (3)
Unconjugated (26)
N-Terminus (16)
aa25-53 (8)
Ligand-binding Domain (7)
aa21-70 (4)
aa264-313 (4)
30-110 aa, N-terminal (1)
aa11-60 (1)
aa20-70 (1)
aa394-404 (1)
No (58)
Yes (1)
EAR2 / NR2F6 Antibody - A: Marker, HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa21-70) Antibody
Mouse, Dog, Bovine, Rat, Pig, Bat, Human
WB
Unconjugated
100 µl/$434
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EAR2 / NR2F6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$411
EAR2 / NR2F6 Antibody - Immunohistochemical analysis of NR2F6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$289
EAR2 / NR2F6 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa264-313) Antibody
Zebrafish, Pig, Bat, Rat, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$404
EAR2 / NR2F6 Antibody - 1:100 staining mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
EAR2 / NR2F6 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using NR2F6 antibody.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$347
EAR2 / NR2F6 Antibody - Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using NR2F6 Antibody. The picture on the right is blocked with the synthesized peptide.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa11-60) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$306; 100 µl/$366
EAR2 / NR2F6 Antibody - Western blot of EAR2 antibody
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µl/$277; 100 µl/$308; 200 µl/$374
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Monkey
IHC, IHC-P
FITC Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody
Human, Monkey
IHC, IHC-P
APC Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (AP) Antibody
Human, Monkey
IHC, IHC-P
AP Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody
Human, Monkey
IHC, IHC-P
PE Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (Biotin) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (FITC) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (Azide-free) (HRP) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (PE) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (AP) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Anti-EAR2 / NR2F6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) (APC) Antibody
Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100 µl/$650
EAR2 / NR2F6 Antibody - Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P
Unconjugated
100 µl/$485
EAR2 / NR2F6 Antibody - Immunohistochemistry image of paraffin-embedded human kidney tissue at a dilution of 1:100
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EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$284; 100 µg/$351
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EAR2 / NR2F6 Mouse anti-Human Monoclonal (EM-51) Antibody
Human
Flo, WB
Unconjugated
0.1 mg/$327
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).