E2F8

E2F transcription factor 8

Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as E2F1: component of a feedback loop in S phase by repressing the expression of E2F1, thereby preventing p53/TP53-dependent apoptosis. Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3). Required for placental development by promoting polyploidization of trophoblast giant cells. Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene.

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Products

Antibodies (26)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (26)

Recombinant (1)

Target

E2F8 (29)

Reactivity

Human (26)

Mouse (2)

Rat (4)

Bat (4)

Bovine (1)

Chimpanzee (3)

Dog (4)

Gibbon (6)

Guinea pig (3)

Hamster (3)

Horse (7)

Monkey (7)

Orangutan (3)

Pig (4)

Rabbit (1)

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Application

IHC (1)

WB (25)

ELISA (9)

IP (2)

Peptide-ELISA (3)

Host

rabbit (18)

mouse (7)

goat (1)

Isotype

IgG (8)

IgG1,k (7)

Clonality

monoclonal mc (7)

polyclonal pc (19)

Clone

3E9-2F5 (1)

Format

AP Conjugated (1)

APC Conjugated (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (11)

Epitope

C-Terminus (8)

N-Terminus (4)

aa402-416 (1)

aa817-867 (1)

aa835-865 (1)

Publications

No (28)

Yes (1)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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E2F8 Antibody LS-C804191

(4.0) Rating

(1) Publication(s)

Antibody:

E2F8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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E2F8 Antibody (C-Terminus) LS-C107893

Antibody:

E2F8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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E2F8 Antibody (C-Terminus, HRP) LS-C450329

Antibody:

E2F8 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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E2F8 Antibody (C-Terminus, Biotin) LS-C450327

Antibody:

E2F8 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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E2F8 Antibody (C-Terminus, FITC) LS-C450328

Antibody:

E2F8 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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E2F8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109829

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94 kDa

Price:

100 µg/$710

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Human E2F8 Protein (Recombinant GST) (Full Length) - LS-G35264

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.15 kDa

Price:

10 µg/$479; 25 µg/$670

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E2F8 Antibody LS-C665253

Antibody:

E2F8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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E2F8 Antibody (clone 3E9-2F5) LS-C307337

Antibody:

E2F8 Mouse anti-Human Monoclonal (3E9-2F5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$655

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E2F8 Antibody (HRP) LS-C541910

Antibody:

E2F8 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$917

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E2F8 Antibody (Biotin) LS-C521777

Antibody:

E2F8 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$917

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E2F8 Antibody (FITC) LS-C531821

Antibody:

E2F8 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$917

Select

E2F8 Antibody (PE) LS-C650022

Antibody:

E2F8 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$917

Select

E2F8 Antibody (AP) LS-C503853

Antibody:

E2F8 Mouse anti-Human Monoclonal (AP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

AP Conjugated

Price:

100 µl/$917

Select

E2F8 Antibody (APC) LS-C513561

Antibody:

E2F8 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$917

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• AP
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • AP
  • APC

Select

E2F8 Antibody LS-C779224

Antibody:

E2F8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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E2F8 Antibody (aa817-867) LS-C286232

Antibody:

E2F8 Rabbit anti-Human Polyclonal (aa817-867) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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E2F8 Antibody (aa835-865) LS-C393015

Antibody:

E2F8 Rabbit anti-Human Polyclonal (aa835-865) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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E2F8 Antibody LS-C331285

Antibody:

E2F8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$377; 200 µl/$503

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E2F8 Antibody (N-Terminus) LS-C201541

Antibody:

E2F8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

E2F8 Antibody (N-Terminus, HRP) LS-C450326

Antibody:

E2F8 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

E2F8 Antibody (N-Terminus, Biotin) LS-C450324

Antibody:

E2F8 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

E2F8 Antibody (N-Terminus, FITC) LS-C450325

Antibody:

E2F8 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

E2F8 Antibody (C-Terminus) LS-C345637

Antibody:

E2F8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

E2F8 Antibody (aa402-416) LS-C112778

Antibody:

E2F8 Goat anti-Human Polyclonal (aa402-416) Antibody

Reactivity:

Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$493

Viewing 1-25 of 29 product results

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