E2F5

E2F transcription factor 5, p130-binding

E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

E2F5 (6)

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No (6)

Tag

His, N-Terminal (1)

Myc-DDK (Flag) (5)

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Human (4)

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293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

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Human E2F5 Protein (Recombinant His, N-Terminal) - LS-G144368

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

37.4 kDa

Price:

50 µg/$419

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E2F5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119809

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

100 µg/$494

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E2F5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118285

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

100 µg/$494

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Human E2F5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67143

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

20 µg/$1,107

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Human E2F5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79221

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

20 µg/$150

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Human E2F5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79222

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.4 kDa

Price:

20 µg/$150

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