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E2F3

E2F transcription factor 3

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner.

Gene Name:	E2F transcription factor 3
Synonyms:	E2F3, E2F transcription factor 3, KIAA0075, Transcription factor E2F3, E2F-3
Target Sequences:	NM_001949 NP_001940.1 O00716

Publications (1)

miR128-1 inhibits the growth of glioblastoma multiforme and glioma stem-like cells via targeting BMI1 and E2F3. Shan ZN, Tian R, Zhang M, Gui ZH, Wu J, Ding M, Zhou XF, He J. Oncotarget. 2016 7:78813-78826. (IF; Human) [Full Text Article] [PubMed:27705931] [PMC:PMC5346679]

Human E2F3 (Sandwich ELISA) ELISA Kit - LS-F9164

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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