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DUSP9

dual specificity phosphatase 9

DUSP9 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.

Gene Name: dual specificity phosphatase 9
Family/Subfamily: Protein Phosphatase , Dual specificity MKP
Synonyms: DUSP9, Dual specificity phosphatase 9, MAP kinase phosphatase 4, MKP-4, MKP4, DUSP 9
Target Sequences: NM_001395 NP_001386.1 Q99956

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
DUSP9 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
DUSP9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41.7 kDa
100 µg/$494
DUSP9 Protein - 12.5% SDS-PAGE of human DUSP9 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.3 kDa
10 µg/$479; 25 µg/$670
DUSP9 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
DUSP9 Protein - Purified recombinant protein DUSP9 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41.7 kDa
20 µg/$1,107
DUSP9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41.7 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).