DUSP8

dual specificity phosphatase 8

DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.

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Products

Antibodies (16)

Type

Primary (16)

Target

DUSP8 (16)

Reactivity

Human (16)

Mouse (5)

Bovine (4)

Gibbon (3)

Hamster (1)

Horse (1)

Monkey (4)

Application

IHC (9)

IHC-P (3)

WB (14)

ELISA (7)

Peptide-ELISA (1)

Host

rabbit (15)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (10)

Clonality

polyclonal pc (16)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (8)

Epitope

aa456-487 (7)

aa359-408 (4)

aa2-14 (1)

aa250-300 (1)

Publications

No (16)

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IHC-plus™ DUSP8 Antibody (aa250-300) LS-B2025

(4.0) Rating

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa250-300) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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DUSP8 Antibody (aa359-408) LS-C111360

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa359-408) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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DUSP8 Antibody (aa359-408, HRP) LS-C455451

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa359-408) (HRP) Antibody

Reactivity:

Mouse, Bovine, Human, Monkey, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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DUSP8 Antibody (aa359-408, Biotin) LS-C455449

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa359-408) (Biotin) Antibody

Reactivity:

Mouse, Bovine, Human, Monkey, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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DUSP8 Antibody (aa359-408, FITC) LS-C455450

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa359-408) (FITC) Antibody

Reactivity:

Mouse, Bovine, Human, Monkey, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ DUSP8 Antibody (aa456-487) LS-B6932

(4.0) Rating

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$440

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DUSP8 Antibody (aa456-487) LS-C330417

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DUSP8 Antibody (aa456-487, Biotin) LS-C225243

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DUSP8 Antibody (aa456-487, FITC) LS-C225244

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DUSP8 Antibody (aa456-487, PE) LS-C225245

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

DUSP8 Antibody (aa456-487, APC) LS-C225242

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DUSP8 Antibody (aa456-487, Azide-free, HRP) LS-C227143

Antibody:

DUSP8 Rabbit anti-Human Polyclonal (aa456-487) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

DUSP8 Antibody LS-C402269

Antibody:

DUSP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DUSP8 Antibody (aa2-14) LS-C54746

Antibody:

DUSP8 Goat anti-Human Polyclonal (aa2-14) Antibody

Reactivity:

Mouse, Bovine, Hamster, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

DUSP8 Antibody LS-C783278

Antibody:

DUSP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$281; 100 µg/$400

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DUSP8 Antibody LS-C816282

Antibody:

DUSP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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