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DUSP16 / MKP7

dual specificity phosphatase 16

MKP7 is a dual specificity MAP kinase phosphatase which has been shown to bind and inactivate kinases p38 (isoforms alpha and beta) and JNK, but not ERK. A mutant form MKP7 has been shown to function as a dominant negative, particularly against the dephosphorylation of JNK in vitro, suggesting that MKP7 works as a JNK-specific phosphatase in vivo. Detailed transcriptional mapping of 12p12 chromosomal region has identified MKP7 as a possible tumor suppressor gene.

Gene Name: dual specificity phosphatase 16
Family/Subfamily: Protein Phosphatase , Dual specificity MKP
Synonyms: DUSP16, MAPK phosphatase-7, MKP7, MAP kinase phosphatase 7, MKP-7, KIAA1700
Target Sequences: AB052156 BAB40814.1 Q9BY84

☰ Filters
Antibodies (20)
Proteins (3)
Over-Expression Lysate (2)
Primary (20)
Recombinant (1)
DUSP16 / MKP7 (23)
Human (20)
Mouse (8)
Rat (3)
Bovine (2)
Dog (1)
Hamster (1)
Horse (1)
Monkey (3)
IHC (7)
IHC-P (5)
WB (12)
ELISA (11)
ICC (2)
IF (7)
Peptide-ELISA (3)
rabbit (13)
mouse (6)
goat (1)
Product Group
IHCPlus (2)
IgG (8)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (14)
APC Conjugated (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (15)
540-620 aa, C-terminal (1)
C-Terminus (1)
aa2-14 (1)
aa561-666 (1)
aa571-620 (1)
aa600-650 (1)
aa70-249 (1)
No (23)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
DUSP16 / MKP7 Antibody - Anti-DUSP16 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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DUSP16 / MKP7 Rabbit anti-Human Polyclonal (aa600-650) Antibody
Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
DUSP16 / MKP7 Antibody - Immunofluorescence analysis of HepG2 cells, using DUSP16 Antibody. The picture on the right is blocked with the synthesized peptide.
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DUSP16 / MKP7 Rabbit anti-Human Polyclonal (aa571-620) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DUSP16 / MKP7 Antibody - Immunohistochemical analysis of DUSP16 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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DUSP16 / MKP7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
DUSP16 / MKP7 Antibody - Anti-DUSP16 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DUSP16 / MKP7 Goat anti-Human Polyclonal (aa2-14) Antibody
Dog, Bovine, Hamster, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal (540-620 aa, C-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DUSP16 / MKP7 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
DUSP16 / MKP7 Antibody - Western blot of Jurkat cell lysate using DUSP16 Antibody
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
DUSP16 / MKP7 Antibody - Peptide - + Immunofluorescence analysis of HepG2 cells, using DUSP16 antibody.
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
DUSP16 / MKP7 Antibody
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal (aa70-249) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
DUSP16 / MKP7 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
DUSP16 / MKP7 Antibody - Staining MCF-7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µl/$386
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (aa561-666) Antibody
Human
ELISA
Unconjugated
100 µg/$705
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µl/$904
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
100 µl/$904
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA
PE Conjugated
100 µl/$904
Select
DUSP16 / MKP7 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$904
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
DUSP16 / MKP7 Antibody - Western blot analysis of extracts of various cell lines, using DUSP16 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
DUSP16 / MKP7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DUSP16 / MKP7 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
DUSP16 / MKP7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
72.9 kDa
20 µg/$215
DUSP16 / MKP7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
72.9 kDa
100 µg/$710
Viewing 1-23 of 23 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).