DUSP11

dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)

DUSP11 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

DUSP11 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human DUSP11 Protein (Recombinant His, N-Terminal) - LS-G144245

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

38.8 kDa

Price:

50 µg/$419

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Human DUSP11 Protein (Recombinant GST) (Full Length) - LS-G31155

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.3 kDa

Price:

2 µg/$439

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Human DUSP11 Protein (Recombinant GST, N-terminus) (aa221-330) - LS-G60724

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human DUSP11 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82617

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.8 kDa

Price:

20 µg/$150

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DUSP11 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100075

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.8 kDa

Price:

100 µg/$494

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