DUOXA1 / NIP

Dual Oxidase Maturation Factor 1

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (8)

Type

Primary (8)

Target

DUOXA1 / NIP (8)

Reactivity

Human (8)

Dog (3)

Pig (3)

Application

WB (4)

ELISA (4)

IF (1)

Host

rabbit (8)

Isotype

IgG (4)

Clonality

polyclonal pc (8)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (2)

Epitope

aa297-346 (4)

Publications

No (8)

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DUOXA1 / NIP Antibody LS-C500106

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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DUOXA1 / NIP Antibody (HRP) LS-C500107

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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DUOXA1 / NIP Antibody (Biotin) LS-C500110

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

DUOXA1 / NIP Antibody (FITC) LS-C500108

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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DUOXA1 / NIP Antibody (aa297-346) LS-C145620

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (aa297-346) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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DUOXA1 / NIP Antibody (aa297-346, HRP) LS-C468388

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (aa297-346) (HRP) Antibody

Reactivity:

Dog, Pig, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DUOXA1 / NIP Antibody (aa297-346, Biotin) LS-C468386

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (aa297-346) (Biotin) Antibody

Reactivity:

Dog, Pig, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DUOXA1 / NIP Antibody (aa297-346, FITC) LS-C468387

Antibody:

DUOXA1 / NIP Rabbit anti-Human Polyclonal (aa297-346) (FITC) Antibody

Reactivity:

Dog, Pig, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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