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DUOX

dual oxidase 1

DUOX is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene Name: dual oxidase 1
Synonyms: DUOX1, DUOX, Flavoprotein NADPH oxidase, Long NOX 1, NOXEF1, Large NOX 1, Thyroid oxidase 1, NADPH thyroid oxidase 1, THOX1, Dual oxidase 1, LNOX1
Target Sequences: NM_017434 NP_059130.2 Q9NRD9

Publications (1)

1
Plasma Membrane Localization of Apoptotic Caspases for Non-apoptotic Functions. Alla Amcheslavsky, Shiuan Wang, Caitlin E Fogarty, Jillian L Lindblad, Yun Fan, Andreas Bergmann. Developmental cell. 2018 May;45:450-464.e3. [Full Text Article] [PubMed:29787709] [PMC:PMC5972739] Related Antibodies: LS-C410118.

☰ Filters
Proteins (5)
Antibodies (4)
ELISA Kits (4)
Custom (3)
Over-Expression Lysate (2)
Primary (4)
Recombinant (3)
Sandwich (1)
DUOX (13)
Human (4)
Mouse (1)
Rat (2)
Dog (1)
Pig (1)
IHC (1)
IHC-P (2)
WB (2)
ELISA (1)
Peptide-ELISA (2)
rabbit (2)
goat (2)
IgG (2)
polyclonal pc (4)
96-Well Strip Plate (4)
Unconjugated (4)
aa1020-1032 (1)
aa972-985 (1)
No (12)
Yes (1)
Plasma (1)
Serum (1)
GST, N-terminus (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
DUOX Antibody - Western blot analysis of extracts of rat heart cells.
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DUOX Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
20 µl/$275; 100 µl/$389
DUOX Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100
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DUOX Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
DUOX Antibody - DUOX1 antibody (0.1 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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DUOX Goat anti-Human Polyclonal (aa972-985) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
DUOX Antibody - Goat Anti-Dual oxidase 1 Antibody (4µg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
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DUOX Goat anti-Human Polyclonal (aa1020-1032) Antibody
Human
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
DUOX Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
177.1 kDa
20 µg/$215
DUOX Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
177.1 kDa
100 µg/$710
DUOX Protein - Purified recombinant protein DUOX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
177.1 kDa
20 µg/$1,107
DUOX Protein - Purified recombinant protein DUOX1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
177.1 kDa
20 µg/$1,107
DUOX ELISA Kit
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Custom
96-Well Strip Plate
Dog
1 Plate/$929
DUOX ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
1 Plate/$783
DUOX ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
1 Plate/$783
DUOX ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
DUOX Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-13 of 13 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).