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Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations By similarity. Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Gene Name: | deltex 4, E3 ubiquitin ligase |
Synonyms: | DTX4, Deltex homolog 4 (Drosophila), Deltex4, KIAA0937, RNF155, Protein deltex-4, RING finger protein 155, Deltex 4 homolog, Deltex 4 homolog (Drosophila) |
Target Sequences: | AF086290 |
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