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DTX2

deltex 2, E3 ubiquitin ligase

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Gene Name: deltex 2, E3 ubiquitin ligase
Synonyms: DTX2, Deltex (Drosophila) homolog 2, Deltex homolog 2 (Drosophila), HDTX2, KIAA1528, Zinc ion binding protein, Protein deltex-2, Deltex2, RING finger protein 58, RNF58
Target Sequences: AB040961 Q6XM87 Q86UW9

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Products
Proteins (11)
Over-Expression Lysate (8)
Recombinant (3)
DTX2 (11)
No (11)
Myc-DDK (Flag) (11)
Human (7)
293T Cells (4)
HEK 293 Cells (7)
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
100 µg/$494
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
100 µg/$710
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
100 µg/$710
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.2 kDa
100 µg/$710
DTX2 Protein - Purified recombinant protein DTX2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$1,107
DTX2 Protein - Purified recombinant protein DTX2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$1,107
DTX2 Protein - Purified recombinant protein DTX2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$1,107
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$215
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$215
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$150
DTX2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.2 kDa
20 µg/$215
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).