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Unfortunately, the antibody (ID:65674) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



DTL / CDT2

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1) and SETD8. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. SETD8 degradation is also important for a proper regulation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.

Gene Name: denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Synonyms: DTL, Denticleless protein homolog, CDT2, DCAF2, CDW1, Denticleless homolog, L2DTL, RAMP
Target Sequences: NM_016448 NP_057532.3 Q9NZJ0

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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF, WB, IP C-Terminus
1
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF, WB, IP C-Terminus No Primary
Anti-DTL / CDT2 Antibody (C-Terminus) LS-C287781
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated, Azide-free,Biotin Conjugated,FITC Conjugated,PE Conjugated,AP Conjugated,APC Conjugated Human, Mouse WB, Flo, ELISA,WB, Flo, ELISA,WB, Flo, ELISA,WB, Flo, ELISA,WB, Flo, ELISA,WB, Flo, ELISA,WB, Flo, ELISA aa229-256
7
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256) LS-C320961
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, Azide-free, HRP) LS-C249871
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free
DTL / CDT2 Rabbit IgG Polyclonal Biotin Conjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, Biotin) LS-C234770
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
Biotin Conjugated
DTL / CDT2 Rabbit IgG Polyclonal FITC Conjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, FITC) LS-C234771
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
FITC Conjugated
DTL / CDT2 Rabbit IgG Polyclonal PE Conjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, PE) LS-C234775
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
PE Conjugated
DTL / CDT2 Rabbit IgG Polyclonal AP Conjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, AP) LS-C234772
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
AP Conjugated
DTL / CDT2 Rabbit IgG Polyclonal APC Conjugated Human, Mouse WB, Flo, ELISA aa229-256 No Primary
Anti-DTL / CDT2 Antibody (aa229-256, APC) LS-C234769
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry, ELISA
APC Conjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human IHC-P, IF, IP aa375-425
1
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human IHC-P, IF, IP aa375-425 No Primary
Anti-DTL / CDT2 Antibody (aa375-425) LS-C287779
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated Human IHC, ELISA,ELISA,ELISA,ELISA
4
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human IHC, ELISA No Primary
Anti-DTL / CDT2 Antibody LS-C501927
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
IHC, ELISA
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal HRP Conjugated Human ELISA No Primary
Anti-DTL / CDT2 Antibody (HRP) LS-C502076
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
ELISA
HRP Conjugated
DTL / CDT2 Rabbit IgG Polyclonal Biotin Conjugated Human ELISA No Primary
Anti-DTL / CDT2 Antibody (Biotin) LS-C502099
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
ELISA
Biotin Conjugated
DTL / CDT2 Rabbit IgG Polyclonal FITC Conjugated Human ELISA No Primary
Anti-DTL / CDT2 Antibody (FITC) LS-C502100
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
ELISA
FITC Conjugated
DTL / CDT2 Rabbit Polyclonal Unconjugated Human, Mouse WB, Flo aa229-256
1
DTL / CDT2 Rabbit Polyclonal Unconjugated Human, Mouse WB, Flo aa229-256 No Primary Available
Anti-DTL / CDT2 Antibody (aa229-256) LS-C167549
Western blot Image
Flow Cytometry Image
Rabbit Polyclonal to Human DTL / CDT2
Human, Mouse
Western blot, Flow Cytometry
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF C-Terminus
1
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF C-Terminus No Primary
Anti-DTL / CDT2 Antibody (C-Terminus) LS-C286712
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Mouse
IHC - Paraffin, Immunofluorescence
Unconjugated
DTL / CDT2 Chicken Polyclonal Unconjugated Human IHC, WB
1
DTL / CDT2 Chicken Polyclonal Unconjugated Human IHC, WB No Primary
Anti-DTL / CDT2 Antibody LS-C96092
Chicken Polyclonal to Human DTL / CDT2
Human
IHC, Western blot
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated,PE Conjugated,AP Conjugated,APC Conjugated Human WB,WB,WB,WB,WB,WB,WB
7
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-DTL / CDT2 Antibody LS-C310175
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal HRP Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (HRP) LS-C541870
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
HRP Conjugated
DTL / CDT2 Rabbit IgG Polyclonal Biotin Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (Biotin) LS-C521739
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
Biotin Conjugated
DTL / CDT2 Rabbit IgG Polyclonal FITC Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (FITC) LS-C531783
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
FITC Conjugated
DTL / CDT2 Rabbit IgG Polyclonal PE Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (PE) LS-C649983
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
PE Conjugated
DTL / CDT2 Rabbit IgG Polyclonal AP Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (AP) LS-C503816
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
AP Conjugated
DTL / CDT2 Rabbit IgG Polyclonal APC Conjugated Human WB No Primary
Anti-DTL / CDT2 Antibody (APC) LS-C513524
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
APC Conjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human WB aa1-196
1
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human WB aa1-196 No Primary
Anti-DTL / CDT2 Antibody (aa1-196) LS-C311890
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human
Western blot
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB,WB,WB,WB aa182-231
4
DTL / CDT2 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa182-231 No Primary Available
Anti-DTL / CDT2 Antibody (aa182-231) LS-C80868
Western blot Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
Unconjugated
DTL / CDT2 Rabbit IgG Polyclonal HRP Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa182-231 No Primary
Anti-DTL / CDT2 Antibody (aa182-231, HRP) LS-C448698
Western blot Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
HRP Conjugated
DTL / CDT2 Rabbit IgG Polyclonal Biotin Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa182-231 No Primary
Anti-DTL / CDT2 Antibody (aa182-231, Biotin) LS-C448696
Western blot Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
Biotin Conjugated
DTL / CDT2 Rabbit IgG Polyclonal FITC Conjugated Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit WB aa182-231 No Primary
Anti-DTL / CDT2 Antibody (aa182-231, FITC) LS-C448697
Western blot Image
Rabbit Polyclonal (IgG) to Human DTL / CDT2
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot
FITC Conjugated
Target Corresponding Antibodies
DTL / CDT2
1
DTL / CDT2 Antibody Blocking Peptide - LS-E634
LS-E634
DTL / CDT2
LS-C167549
DTL / CDT2
1
DTL / CDT2 Antibody Blocking Peptide - LS-E16871
LS-E16871
DTL / CDT2
LS-C80868
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant DTL / CDT2 None E. coli
1
DTL / CDT2 Protein (Recombinant) - LS-G41815
E. coli Expression System
None
Lyophilized
Recombinant DTL / CDT2 None E. coli
1
DTL / CDT2 Protein (Recombinant) - LS-G41816
E. coli Expression System
None
Lyophilized

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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