DSP / Desmoplakin

desmoplakin

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

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Proteins (4)

Type

Recombinant (4)

Target

DSP / Desmoplakin (4)

Publications

No (4)

Tag

His (3)

His-SUMO (1)

Species

Human (3)

Mouse (1)

Source

E. coli (3)

Yeast (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human DSP / Desmoplakin Protein (Recombinant His) (aa78-300) - LS-G22894

Source:

Yeast

Tag:

His

Molecular Weight:

28.06 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human DSP / Desmoplakin Protein (Recombinant His) (aa2609-2822) - LS-G24685

Source:

E. coli

Tag:

His

Molecular Weight:

27.0 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human DSP / Desmoplakin Protein (Recombinant His-SUMO) (aa78-300) - LS-G20680

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

42 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse DSP / Desmoplakin Protein (Recombinant His) (aa1808-2058) - LS-G140948

Source:

E. coli

Sequence Length:

250 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

27.61 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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