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DSC3 / Desmocollin 3

desmocollin 3

DSC3 / Desmocollin 3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: desmocollin 3
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: DSC3, CDHF3, Cadherin family member 3, Desmocollin-3, Desmocollin 3, DSC4, HT-CP, Desmocollin-4, DSC
Target Sequences: NM_001941 NP_001932.2 Q14574

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ELISA Kits (2)
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DSC3 / Desmocollin 3 (2)
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Cell Culture Supernatants (1)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
DSC3 / Desmocollin 3 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.16 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
DSC3 / Desmocollin 3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).