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DSC1 / Desmocollin 1

desmocollin 1

DSC1 / Desmocollin 1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Gene Name: desmocollin 1
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: DSC1, Desmocollin-1, Desmocollin 1, Desmosomal glycoprotein 2/3, DG2/DG3, Cadherin family member 1, CDHF1
Target Sequences: NM_024421 NP_077739.1 Q08554

Publications (1)

1
BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality. Ikawa-Yoshida A, Matsumoto T, Okano S, Aoyagi Y, Matsubara Y, Furuyama T, Nakatsu Y, Tsuzuki T, Onimaru M, Ohkusa T, Nomura M, Maehara Y. Scientific reports. 2016 6:32399. (WB; Human) [Full Text Article] [PubMed:27561386] [PMC:PMC4999951] Related Antibodies: LS-C167539.

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Antibodies (30)
Primary (30)
DSC1 / Desmocollin 1 (30)
Human (22)
Mouse (11)
Rat (1)
IHC (6)
IHC-Fr (1)
IHC-P (4)
WB (27)
Flo (1)
ELISA (9)
rabbit (28)
mouse (2)
Product Group
IHCPlus (1)
IgG (10)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (28)
Dsc1-U100 (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (11)
aa135-340 (8)
aa486-686 (8)
aa659-687 (7)
Intracellular (1)
No (29)
Yes (1)
DSC1 / Desmocollin 1 Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with DSC1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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DSC1 / Desmocollin 1 Mouse anti-Human Monoclonal (Intracellular) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$939
DSC1 / Desmocollin 1 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
DSC1 / Desmocollin 1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using DSC1 Polyclonal Antibody at dilution of 1:40.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant protein.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa486-686) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant protein.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa486-686) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant protein.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa486-686) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
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DSC1 / Desmocollin 1 Mouse anti-Human Monoclonal (Dsc1-U100) Antibody
Human
IHC, WB
Unconjugated
50 µg/$755
DSC1 / Desmocollin 1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
DSC1 / Desmocollin 1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using DSC1 Polyclonal Antibody at dilution of 1:40.
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal (aa659-687) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
DSC1 / Desmocollin 1 Antibody - Western Blot; Sample: Recombinant DSC1, Mouse.
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DSC1 / Desmocollin 1 Rabbit anti-Mouse Polyclonal (aa135-340) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
DSC1 / Desmocollin 1 Antibody
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DSC1 / Desmocollin 1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).