DROSHA / RNASEN

drosha, ribonuclease type III

Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

☰ Filters

Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

DROSHA / RNASEN (4)

Publications

No (4)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Purification

Purified (1)

Select

Human DROSHA / RNASEN Protein (Recombinant His, N-Terminal) (Ile1114-Glu1235) - LS-G15192

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

Select

Human DROSHA / RNASEN Protein (Recombinant GST) - LS-G132166

Tag:

GST

Molecular Weight:

36.52kDa

Price:

10 µg/$479; 25 µg/$670

Select

DROSHA / RNASEN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114387

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

159.1 kDa

Price:

100 µg/$710

Select

Human DROSHA / RNASEN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83586

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

159.1 kDa

Price:

20 µg/$215

Viewing 1-4 of 4 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.