DROSHA / RNASEN

drosha, ribonuclease type III

Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

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Products

ELISA Kits (5)

Type

Sandwich (4)

Sandwich CLIA (1)

Target

DROSHA / RNASEN (5)

Reactivity

Human (4)

Monkey (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (3)

Publications

No (5)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Human DROSHA / RNASEN (Sandwich ELISA) ELISA Kit - LS-F7638

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Monkey DROSHA / RNASEN (Sandwich ELISA) ELISA Kit - LS-F47788

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human DROSHA / RNASEN (Sandwich ELISA) ELISA Kit - LS-F22198

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human DROSHA / RNASEN (CLIA) ELISA Kit - LS-F30378

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human DROSHA / RNASEN (Sandwich ELISA) ELISA Kit - LS-F36359

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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