DROSHA / RNASEN

drosha, ribonuclease type III

Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

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Products

Antibodies (33)

ELISA Kits (5)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (33)

Recombinant (2)

Sandwich (4)

Sandwich CLIA (1)

Target

DROSHA / RNASEN (42)

Reactivity

Human (37)

Mouse (11)

Rat (3)

Bat (1)

Bovine (1)

Chimpanzee (3)

Dog (1)

Guinea pig (3)

Hamster (1)

Horse (1)

Monkey (3)

Pig (1)

Rabbit (4)

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Application

IHC (3)

WB (31)

ELISA (9)

IP (1)

Peptide-ELISA (3)

Host

rabbit (32)

goat (1)

Isotype

IgG (16)

Clonality

polyclonal pc (33)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (3)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Preservative Free (1)

Unconjugated (18)

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Epitope

aa1114-1235 (8)

aa737-764 (7)

C-Terminus (4)

Internal (1)

aa1050-1100 (1)

aa1324-1374 (1)

aa774-823 (1)

aa811-822 (1)

Publications

No (42)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Purification

Purified (1)

Select

Human DROSHA / RNASEN Protein (Recombinant His, N-Terminal) (Ile1114-Glu1235) - LS-G15192

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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DROSHA / RNASEN Antibody (aa811-822) LS-C55399

Antibody:

DROSHA / RNASEN Goat anti-Human Polyclonal (aa811-822) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Hamster, Pig, Horse, Bat, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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DROSHA / RNASEN Antibody (Internal) LS-C353409

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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Human DROSHA / RNASEN (Sandwich ELISA) ELISA Kit - LS-F7638

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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DROSHA / RNASEN Antibody LS-C813502

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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DROSHA / RNASEN Antibody (aa737-764) LS-C324712

Antibody:

DROSHA / RNASEN Rabbit anti-Mouse Polyclonal (aa737-764) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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DROSHA / RNASEN Antibody (aa737-764, Biotin) LS-C268358

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa737-764) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DROSHA / RNASEN Antibody (aa737-764, FITC) LS-C268359

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa737-764) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DROSHA / RNASEN Antibody (aa737-764, APC) LS-C268357

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa737-764) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DROSHA / RNASEN Antibody (aa737-764, Azide-free, HRP) LS-C268361

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa737-764) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DROSHA / RNASEN Antibody (aa737-764, PE) LS-C268360

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa737-764) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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DROSHA / RNASEN Antibody LS-C830025

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DROSHA / RNASEN Antibody LS-C665207

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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DROSHA / RNASEN Antibody (aa1050-1100) LS-C286621

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa1050-1100) Antibody

Reactivity:

Mouse, Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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DROSHA / RNASEN Antibody (aa1324-1374) LS-C288663

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa1324-1374) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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DROSHA / RNASEN Antibody (aa774-823) LS-C291732

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa774-823) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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DROSHA / RNASEN Antibody LS-C807257

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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DROSHA / RNASEN Antibody (aa737-764) LS-C158243

Antibody:

DROSHA / RNASEN Rabbit anti-Mouse Polyclonal (aa737-764) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DROSHA / RNASEN Antibody LS-C314094

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

DROSHA / RNASEN Antibody LS-C766171

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

DROSHA / RNASEN Antibody (C-Terminus) LS-C110561

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DROSHA / RNASEN Antibody (aa1114-1235) LS-C296275

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (aa1114-1235) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

DROSHA / RNASEN Antibody LS-C412187

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

DROSHA / RNASEN Antibody LS-C409872

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

DROSHA / RNASEN Antibody (Preservative Free) LS-C814800

Antibody:

DROSHA / RNASEN Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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