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DRAP1

DR1-associated protein 1 (negative cofactor 2 alpha)

Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.

Gene Name: DR1-associated protein 1 (negative cofactor 2 alpha)
Synonyms: DRAP1, Nc2 alpha subunit, NC2-alpha, Negative cofactor 2 alpha, Dr1-associated corepressor, Dr1-associated protein 1, Negative co-factor 2-alpha
Target Sequences: NM_006442 NP_006433.2 Q14919

☰ Filters
Antibodies (18)
Proteins (6)
Over-Expression Lysate (2)
Primary (18)
Recombinant (4)
DRAP1 (24)
Human (18)
Mouse (3)
Rat (3)
Bat (3)
Bovine (3)
Chimpanzee (3)
Goat (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
Xenopus (3)
Zebrafish (3)
IHC (5)
WB (18)
ELISA (13)
IF (1)
rabbit (16)
mouse (2)
IgG (15)
IgG1 (1)
IgG2a (1)
monoclonal mc (2)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (7)
aa1-29 (7)
N-Terminus (4)
No (24)
GST (2)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Select
DRAP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
DRAP1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DRAP1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DRAP1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
DRAP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
Select
DRAP1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
150 µg/$842
Select
DRAP1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
150 µg/$842
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
DRAP1 Antibody - DRAP1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRAP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DRAP1 Antibody - DRAP1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRAP1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Goat, Guinea pig, Bovine, Bat, Rat, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
DRAP1 Antibody - DRAP1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRAP1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Goat, Guinea pig, Bovine, Bat, Rat, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
DRAP1 Antibody - DRAP1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DRAP1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Goat, Guinea pig, Bovine, Bat, Rat, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
DRAP1 Antibody - DRAP1 Antibody western blot of A2058 cell line lysates (35 ug/lane). The DRAP1 antibody detected the DRAP1 protein (arrow).
Select
DRAP1 Rabbit anti-Human Polyclonal (aa1-29) Antibody
Human
WB
Unconjugated
400 µl/$393
DRAP1 Protein - Purified recombinant protein DRAP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
22.2 kDa
20 µg/$1,107
DRAP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
GST
48.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
DRAP1 Protein - 12.5% SDS-PAGE of human DRAP1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
48.7 kDa
10 µg/$479; 25 µg/$670
DRAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.2 kDa
100 µg/$494
DRAP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.2 kDa
20 µg/$150
Viewing 1-24 of 24 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).