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DPYSL3 / CRMP4

dihydropyrimidinase-like 3

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.

Gene Name: dihydropyrimidinase-like 3
Synonyms: DPYSL3, CRMP4, CRMP-4, DRP3, DRP-3, LCRMP, ULIP1, Unc-33-like phosphoprotein 1, ULIP, ULIP-1, Dihydropyrimidinase-like 3
Target Sequences: NM_001387 NP_001378.1 Q14195

Publications (2)

1
Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer. Kanda M, Nomoto S, Oya H, Shimizu D, Takami H, Hibino S, Hashimoto R, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y. Journal of experimental & clinical cancer research : CR. 2014 33:66. (WB; Human) [Full Text Article] [PubMed:25096402] [PMC:PMC4431488] Related Antibodies: LS-C133161.
2
Diabetes, an independent poor prognostic factor of non-B non-C hepatocellular carcinoma, correlates with dihydropyrimidinase-like 3 promoter methylation. Satoko Umetsu, Hiroki Mizukami, Takeshi Saito, Chiaki Uchida, Akiko Igawa, Kazuhiro Kudo, Chieko Itabashi, Sho Osonoi, Guo Danyang, Takanori Sasaki, Soroku Yagihashi, Kenichi Hakamada. Scientific reports. 2020 Jan;10:1156. [Full Text Article] [PubMed:31980687] [PMC:PMC6981134] Related Antibodies: LS-C133161.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).