DPH5

diphthamide biosynthesis 5

DPH5 is a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (6)

Antibodies (2)

Type

Over-Expression Lysate (4)

Primary (2)

Recombinant (2)

Target

DPH5 (8)

Reactivity

Human (2)

Application

IHC-P (1)

WB (1)

Host

rabbit (1)

mouse (1)

Isotype

IgG (2)

Clonality

polyclonal pc (2)

Format

Unconjugated (2)

Publications

No (8)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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DPH5 Antibody LS-C816274

Antibody:

DPH5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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DPH5 Antibody LS-C307299

Antibody:

DPH5 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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Human DPH5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71611

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.5 kDa

Price:

20 µg/$1,107

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Human DPH5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90199

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.4 kDa

Price:

20 µg/$150

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Human DPH5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90200

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.5 kDa

Price:

20 µg/$150

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Human DPH5 Protein (Recombinant GST) (Full Length) - LS-G33841

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.1 kDa

Price:

10 µg/$479; 25 µg/$670

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DPH5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112982

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.5 kDa

Price:

100 µg/$494

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DPH5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119978

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.4 kDa

Price:

100 µg/$494

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