DOK1

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

DOK1 (6)

Publications

No (6)

Tag

GST (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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DOK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118639

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.2 kDa

Price:

100 µg/$710

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Human DOK1 Protein (Recombinant His-SUMO) (Full Length) - LS-G21896

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

68.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Rat DOK1 Protein (Recombinant His-T7) (aa18-237) - LS-G24856

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.0 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human DOK1 Protein (Recombinant GST) (Full Length) - LS-G28240

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human DOK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76091

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.2 kDa

Price:

20 µg/$215

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Human DOK1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65703

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.2 kDa

Price:

20 µg/$1,107

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